The role of biomarkers and genetics in peripheral arterial disease.

The role of miRNAs as diagnostic and therapeutic biomarkers in various cancers

According to the growing number of cancer fatalities and the complexity of the disease in diagnosis, prognosis and treatment, here we have reviewed one of the helpful and promising factors in the diagnosis and treatment of cancer. Micro-ribonucleic acids (miRNAs) are non-coding ribonucleic acids that are evolutionarily conserved and have a length of 18-25 nucleotides. miRNAs control the express...

The Role of Inflammatory Biomarkers in the Management of Children with Asthma

Background Making decision on asthma as an inflammatory disease is done mostly on the airways function and the patient symptoms which most of them are nonspecific and subjective. Also, the children are not able to express their signs and collaboration in examination of the lungs function. Evaluation of serum level inflammatory biomarkers can be useful in assessment of the response to treatment ...

Circulating microRNA profiles for detection of peripheral arterial disease: small new biomarkers for cardiovascular disease.

Prevalence of Peripheral Arterial Disease in Diabetic Patients

Objective: Peripheral Arterial Disease (PAD) is a state characterized by atherosclerotic occlusive disease of lower extremities. Diabetes is the main risk factor for PAD. Material and Methods: To assess the prevalence of PAD, a cross sectional study was performed on 352 diabetic patients who referred to Yazd diabetes research center from 2007 to 2010. Vascular assessment was done by measuring ...

The role of biomarkers in the diagnosis and differentiation of thyroid cancers

Thyroid cancer is one of the most common endocrine cancers in the body, which accounts for approximately 1.8% of all malignancies in Iran and its prevalence is reported to be higher among women than men .This type of cancer is classified into four main subgroups including papillary (PTC), follicular (FTC), medullary (MTC) and Anaplastic (ATC).To differentiate different types of cancer, biopsy m...

Circulating miR-193b-3p and miR-376a-3p Involved in Iranian Patients with Multiple Sclerosis

Multiple sclerosis (MS) is an inflammatory disease that affects the central nervous system. MicroRNAs (miRNAs) are small non-coding RNAs that are usually 18-24 nucleotides long, which may have a pivotal role in the expansion of many complex diseases. The objective of this study was to evaluate the transcript levels of miR-193b-3p and miR-376a-3p in relapsing-remitting multiple sclerosis (RRMS) ...